ME/CFS Metabolic Features

The study “Metabolic Features of Chronic Fatigue Syndrome” published by Naviaux RK, et al. is a landmark in ME / CFS research. It is the most important and groundbreaking study of ME / CFS to date. Extending recent indications of metabolic alterations in ME / CFS, this study provides the first comprehensive, quantitative demonstration of the metabolomic deficiencies that characterize the disease.

They define a clear metabolic ‘signature’ that accurately distinguishes patients from healthy individuals. This signature was consistent even among patients with different symptoms or disease-initiating events. These findings are exciting news for both patients and researchers.